GLUTARALDEHYDE TANNED OVINE COLLAGEN COMPARED WITH POLYTETRAFLUOROETHYLENE (GORE‐TEX) AS A CONDUIT FOR SMALL CALIBRE ARTERY SUBSTITUTION; AN EXPERIMENTAL STUDY IN DOGS
- 1 December 1981
- journal article
- research article
- Published by Wiley in Anz Journal of Surgery
- Vol. 51 (6) , 556-561
- https://doi.org/10.1111/j.1445-2197.1981.tb05254.x
Abstract
Collagen tubes with a polyester mesh endoskeleton were grown in sheep around silastic mandrils and were then tanned in alkaline glutaraldehyde. Tanned ovine collagen conduits and polytetrafluoroethylene conduits (Gore-Tex), each 10 cm long and 6 mm wide, were deployed in parallel as aorto-iliac bypass grafts in 10 dogs. The grafts remained patient for periods up to and exceeding 23 mo. No grafts showed aneurysmal dilatation. All grafts formed a neointima lined with cells. In the Gore-Tex grafts there was fibrous tissue ingrowth through the wall which resulted in progressive and irregular luminal narrowing. This was not seen in the tanned ovine collagen grafts.This publication has 4 references indexed in Scilit:
- Glutaraldehyde-Tanned Ovine Collagen Conduits as Vascular Xenografts in DogsArchives of Surgery, 1980
- Patency rates of minute vascular replacements: The glutaraldehyde modified mandril-grown conduitJournal of Surgical Research, 1980
- Dilation of Synthetic Grafts and Junctional AneurysmsArchives of Surgery, 1979
- A Small Arterial substituteAnnals of Surgery, 1975