Decreased striatal dopaminergic innervation in REM sleep behavior disorder
- 14 November 2000
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 55 (9) , 1410-1412
- https://doi.org/10.1212/wnl.55.9.1410
Abstract
Article abstract—REM sleep behavior disorder (RBD) is a possible herald of neurodegenerative disorders with parkinsonism. The authors determined the density of striatal dopaminergic terminals with [11C]dihydrotetrabenazine PET in six elderly subjects with chronic idiopathic RBD and 19 age-appropriate controls. In subjects with RBD, there were significant reductions in striatal [11C]dihydrotetrabenazine binding, particularly in the posterior putamen.Keywords
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