Effects of the Prosegment and pH on the Activity of PCSK9
Open Access
- 1 December 2010
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 285 (52) , 40965-40978
- https://doi.org/10.1074/jbc.m110.154815
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptorProceedings of the National Academy of Sciences, 2008
- Molecular basis for LDL receptor recognition by PCSK9Proceedings of the National Academy of Sciences, 2008
- Self-Association of Human PCSK9 Correlates with Its LDLR-Degrading ActivityBiochemistry, 2008
- The self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domainProceedings of the National Academy of Sciences, 2007
- Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activityBiochemical Journal, 2007
- Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of ChylomicronsCell Metabolism, 2007
- Molecular biology of PCSK9: its role in LDL metabolismTrends in Biochemical Sciences, 2007
- Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotypeProceedings of the National Academy of Sciences, 2004
- Mutations in PCSK9 cause autosomal dominant hypercholesterolemiaNature Genetics, 2003
- The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiationProceedings of the National Academy of Sciences, 2003