Dopamine transporter imaging study in parkinsonism occurring in fragile X premutation carriers
- 27 December 2005
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 65 (12) , 1971-1973
- https://doi.org/10.1212/01.wnl.0000188821.51055.52
Abstract
The authors studied four patients with parkinsonism carrying the fragile X premutation using SPECT with [23I]FP-CIT. They found evidence of preserved presynaptic nigrostriatal function, suggesting that parkinsonism in the X fragile premutation might be related to postsynaptic dopaminergic changes or different neurotransmitter alterations.Keywords
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