Detection of Breast Cancer Microcalcifications Using a Dual-modality SPECT/NIR Fluorescent Probe

4 December 2008

journal article
research article
Published by American Chemical Society (ACS) in Journal of the American Chemical Society

Vol. 130 (52) , 17648-17649
https://doi.org/10.1021/ja807099s

Abstract

Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneous in vivo imaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the “gold standard” by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized.

Keywords

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