Drug metabolism and disposition in children
- 3 June 2003
- journal article
- review article
- Published by Wiley in Fundamental & Clinical Pharmacology
- Vol. 17 (3) , 281-299
- https://doi.org/10.1046/j.1472-8206.2003.00140.x
Abstract
Key factors undergoing maturational changes accounting for differences in drug metabolism and disposition in the pediatric population compared with adults are reviewed. Gastric and duodenal pH, gastr...Keywords
This publication has 153 references indexed in Scilit:
- The dose response of theophylline in the treatment of apnea of prematurityThe Journal of Pediatrics, 1988
- Absorption characteristics of once-a-day slow-release theophylline preparation in children with asthmaThe Journal of Pediatrics, 1987
- Inconsistent absorption from a susstained-release theophylline preparation during continuous therapy in asthmatic childrenThe Journal of Pediatrics, 1985
- Dosing implications of rapid elimination of trimethoprim-sulfamethoxazole in patients with cystic fibrosisThe Journal of Pediatrics, 1984
- Pharmacokinetics and antipruritic effects of hydroxyzine in children with atopic dermatitisThe Journal of Pediatrics, 1984
- Pharmacokinetics of chloramphenicol and chloramphenicol succinate in infants and childrenThe Journal of Pediatrics, 1981
- Caffeine, a metabolite of theophylline during the treatment of apnea in the premature infantThe Journal of Pediatrics, 1979
- Metabolism of theophylline to caffeine in premature newborn infantsThe Journal of Pediatrics, 1979
- Age-related differences in salicylamide and acetaminophen conjugation in manThe Journal of Pediatrics, 1977
- Glomerular filtration rate, effective renal bloodflow, and maximal tubular excretory capacity in infancyThe Journal of Pediatrics, 1948