Enumeration of immune interferon-producing cells induced by allogeneic stimulation

Abstract
Immune interferon-producing cells [mouse] induced by allogeneic stimulation were enumerated and it was proved that they were T [thymus-derived] lymphocytes. The peak level of these cells in spleen was attained on day 5 after immunization, was maintained for about 2 days and declined thereafter. Titers of interferon produced in vitro by sensitized spleen cells were maximum on day 7. Maturation of immune interferon-producing cells may follow cell proliferation after antigen stimulation.

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