DISTURBANCE OF OESTROUS CYCLES IN RATS FOLLOWING ADMINISTRATION OF FREUND'S COMPLETE ADJUVANT

Publisher Website
Google Scholar
Abstract
Female rats injected with Freund''s complete adjuvant in the hind limb footpads had abnormal estrous cycles characterized by prolonged leucocytic phases. This was observed within 2 days in some animals given adjuvant on the 1st day of diestrus. About one-fourth of the animals with abnormal cycles had the same number of continuous L-days as animals made pseudo-pregnant by electrical stimulation (11 to 16 days). Although electrical stimulation of the cervix induced pseudopregnancy optimally when applied at proestrus, adjuvant induced pseudopregnancy equally well whether injected at proestrus or diestrus.

This publication has 4 references indexed in Scilit: