THROMBOGENICITY OF COMPONENTS OF ATHEROMATOUS MATERIAL - AN ANIMAL AND INVITRO MODEL OF CEREBRAL ATHEROEMBOLISM
- 1 January 1981
- journal article
- research article
- Vol. 105 (7) , 353-357
Abstract
Human atheromatous material was separated into lipid and nonlipid fractions by ether and chloroform-methyl alcohol procedures. The maximum nonlethal doses of nonlipid, lipid and whole (unseparated) atheromatous material were 8, 15-30 and 50-60 mg, respectively, when injected into the left common carotid arteries of rabbits. In vitro production of thrombi showed that the nonlipid material produced thrombi that were larger in volume, weight and length than those produced by whole material.This publication has 4 references indexed in Scilit:
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