Undifferentiated carcinoma of the large intestine

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Abstract
Eight cases of undifferentiated carcinoma of the large intestine are described. The histological distinction between undifferentiated and poorly differentiated colonic adenocarinoma and malignant carcinoid is discussed. Undifferentiated carcinoma is a variant of adenocarcinoma which grows to a large size before symptoms are produced but which has a good prognosis when locally resectable. Five patients survived between 6 and 28 yr, 1 is well 6 mo. after operation and 2 cases where local removal could not be achieved died within a year.

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