Localization of 3H-Prazosin Binding Sites in the Supraoptic and Paraventricular Nuclei of the Human Hypothalamus
- 1 January 1990
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 51 (3) , 315-319
- https://doi.org/10.1159/000125355
Abstract
Using 3H-prazosin, we have examined the distribution of α1-adrenergic receptors in the supraoptic and paraventricular nuclei of the human hypothalamus. Our studies show that binding sites for 3H-prazosin in human hypothalamus possess pharmacological characteristics similar to those of rat brain. Autoradiographic studies revealed discrete localization of 3H-prazosin to the paraventricular and supraoptic nuclei.Keywords
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