Lipids and Lipoproteins in Chronic Uraemia. A Study of the Influence of Regular Haemodialysis**
- 1 February 1976
- journal article
- research article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 6 (1) , 159-166
- https://doi.org/10.1111/j.1365-2362.1976.tb00507.x
Abstract
Plasma lipids and lipoproteins were studied in a group of chronic uraemic patients seme of whan were maintained by regular haemodialysis. Compared with healthy individuals, there was a significant increase in plasma triglycerides and in the prebeta‐1‐ and prebeta‐2‐lipoprotein plasma concentrations. There was no difference between dialyzed and undialyzed patients. Carbohydrate intake was normal, basal plasma insulin and free fatty acid levels were within the normal range. There was no correlation between plasma triglyceride levels and the degree of hypoalbuminaemia, the latter being marked in 30% of the patients. Basal plasma glucagon levels were very high in nearly all dialyzed patients and post‐heparin lipoprotein‐lipase activity was very low in dialyzed patients. In our experience, regular haemodialysis for 32 weeks did not improve hypertriglyceridaemia.Keywords
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