Serum Creatine Phosphokinase Activity After Intramuscular Injection
- 30 September 1974
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 229 (14) , 1894-1897
- https://doi.org/10.1001/jama.1974.03230520036027
Abstract
Solutions of two compounds, pralidoxime chloride and sodium chloride, were given intramuscularly to normal human subjects. The ensuing increase in creatine phosphokinase (CPK) activity in the blood was directly related to the concentration and osmolarity of the injected solution when the volume was kept constant, and directly related to the volume when the concentration or osmolarity was kept constant. These findings suggest that the diluent may make a significant contribution to the increase in CPK observed after intramuscular administration of drugs. (JAMA229:1894-1897, 1974)Keywords
This publication has 3 references indexed in Scilit:
- Pain and CPK Elevation after Intramuscular DigoxinNew England Journal of Medicine, 1973
- Elevated Serum CPK after Drug InjectionsNew England Journal of Medicine, 1972
- Effect of Intramuscular Injections on Serum Creatine Phosphokinase ActivityThe Lancet Healthy Longevity, 1970