The Q Waves of Hypertrophic Cardiomyopathy

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Abstract
IN patients with hypertrophic cardiomyopathy the electrocardiogram often displays deep Q waves that may suggest myocardial infarction.1 2 3 Some investigators have ascribed these Q waves to the activation of the hypertrophied interventricular septum,4 , 5 but others think that they may be due to fibrosis of the septal tissue.6 We have performed an electrophysiologic study of ventricular activation in six patients with hypertrophic cardiomyopathy, normal coronary arteries, and deep Q waves on the electrocardiogram. Our findings suggest that the Q waves are produced by the activation of the septum and that myopathic septal muscle has different electrophysiologic properties from those of the remainder . . .