Cyproterone Acetate for Male Hypersexuality

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Abstract
The efficacy of cyproterone acetate in the treatment of sexual overactivity has been assessed in fifty male patients over a period of five years. Homosexual activity was reduced in its intensity but not in its direction. Masturbation was diminished in subnormal and chronic schizophrenic patients and there was a social improvement in elderly men guilty of sexual misbehaviour. Two sado-masochists showed greater clinical improvement when cyproterone acetate was added to psychotherapy than occurred with the latter therapy alone. Physical aggression exhibited by two subnormal patients which was resistant to conventional therapy, responded dramatically to cyproterone acetate administration. There were no significant side-effects.