Synthesis of TN and Sialyl TH Antigen-Lipid A Analog Conjugates for Synthetic Vaccines.

Abstract
Conjugates of Tn and sialyl Tn antigen with N-teradecanoyl L-seryl-beta-alanine-containing D-glucosamine derivatives structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers or HIV.

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