USE OF THIOURACIL IN THE PREOPERATIVE PREPARATION OF PATIENTS WITH SEVERE HYPERTHYROIDISM

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Abstract
Further experience with the use of thiouracil in 64 cases confirms an early impression that this drug is extremely valuable in the preoperative management of patients with severe primary hyperthyroidism or ade-nomatous goiter with secondary hyperthyroidism. Thiouracil should be administered until maximum benefit is obtained, and at that time operation can then be carried out without risk. The technical difficulties at operation which occurred in patients treated only with thiouracil have now been overcome by the added use of Lugol''s soln. during a 3-wk. period immediately before operation. The value of thiouracil lies in the reduction of the risk of surgical treatment which is still needed to terminate hyperthyroidism with greater certainty and greater safety.

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