Uterotrophic Effect of Digoxin Administration in the Rat.
- 1 June 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 95 (2) , 234-238
- https://doi.org/10.3181/00379727-95-23177
Abstract
Ovariectomized rats were treated with doses of estrone (0.1 mg), digoxin (2.0 mg/kg) and both drugs for 7 days. Digoxin administration resulted in uterotrophic response evidenced by heightening of epithelium and enlargement of epithelial nuclei; edema of the stroma with vesicula-tion of the stromal nuclei and prominence of stromal nucleoli, and recovery of the myometrium from a castrate condition. The response of castrate uteri to estrone was intensified by concurrent digoxin administration.Keywords
This publication has 0 references indexed in Scilit: