Serological studies on infections by respiratory viruses of the inhabitants of Tristan da Cunha

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Abstract
Sera were obtained from about half of the Tristan da Cunha islanders on reaching Cape Town in October 1961, a few months after reaching Britain and before returning to the Island in 1963. After vaccination against current influenza A 2 and B serotypes antibodies were evoked against earlier serotypes, in particular against influenza A1 of 1951 with which the islanders had almost certainly been infected. Those who failed to develop antibody against A 2 and B after vaccination developed it later presumably owing to natural infection. Almost all islanders developed antibodies against parainfluenza 3 and 1 and some against parainfluenza 2 and coxsackie A 21 viruses. There were no antibody rises against reoviruses.