PAIN RELIEF IN THE RHEUMATOID KNEE AFTER STEROID INJECTION A SINGLE-BLIND COMPARISON OF HYDROCORTISONE SUCCINATE, AND TRIAMCINOLONE ACETONIDE OR HEXACETONIDE
- 1 May 1994
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 33 (5) , 461-463
- https://doi.org/10.1093/rheumatology/33.5.461
Abstract
Since the introduction of intra-articular steroid therapy 40 yr ago there have been many changes in the treatment of rheumatoid patients. Previous studies suggest differing times of response for the same agents. This study reports the response, measured by a five-point pain chart, of 300 patients with painful rheumatoid knees. Sixty received hydrocortisone succinate (HC), 150 received triamcinolone acetonide (TA), and 120 triamcinolone hexacetonide (TH). Results demonstrated little effect with HC, but good responses with TA and TH. More patients were rendered painfree for a longer time with TH; 18% at 12 weeks, as against 9% with TA (χ2 test P2 test P<0.05). TH is the preferred preparation for injection of the rheumatoid knee.Keywords
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