Studies on Calcium Regulation in Relation to Sodium Potassium Balance in the Rabbit Lens

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Abstract
Net changes in the levels of lens Ca, Mg, Na, K and water content were determined following exposure in vitro to iodoacetate, ouabain, La, cyanide, quercetin and cold temperature. The lens Ca content rose following inhibition of lens metabolism but did not change following specific inhibition of the Na pump. Apparently regulation of the lens Ca balance is largely independent of lens Na and K content. A greater increase in lens Na content upon iodoacetate treatment vs. oubain treatment is discussed in relation to the elevation of lens Ca.