Collateral bronchopulmonary circulation after spontaneous recanalisation of pulmonary thromboemboli in the dog

Publisher Website
Google Scholar
Abstract
Study objective – The aim was to study the fate of enlarged bronchial arteries after resolution of experimental pulmonary embolism. Design – Embolisation of the pulmonary arteries of both lungs was performed with intravenous gelfoam. Pulmonary pressure and pulmonary arteriolar resistance were measured 1 h, 40 d and 80 d after embolisation. Pulmonary angiography and aortography were performed at the same time to evaluate the pulmonary emboli and the collateral bronchopulmonary circulation. Aortography and gross pathological and histological examination of the lungs was performed after 80 d. Experimental material – 15 adult mongrel dogs of either sex were studied, weight 22-25 kg. Nine dogs were embolised and there were six controls. Measurements and main results – All animals survived until 80 d. There was a rise (pConclusions – Our data show a temporal dissociation between the resolution of pulmonary thromboemboli in the present model and the eventual regression of developed bronchopulmonary collateral vessels. The mechanism of this dissociation could not be elucidated.