Conformational changes accompanying proteolytic cleavage of human complement protein C3b by the regulatory enzyme factor I and its cofactor H. Spectroscopic and enzymological studies.
Open Access
- 1 April 1983
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 258 (7) , 4238-4244
- https://doi.org/10.1016/s0021-9258(18)32612-7
Abstract
No abstract availableThis publication has 39 references indexed in Scilit:
- Conformational and functional changes in the fourth component of human complement produced by nucleophilic modification and by proteolysis with C1.lovin.sBiochemistry, 1982
- Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3.The Journal of Experimental Medicine, 1981
- The Proteolytic Activation Systems of ComplementAnnual Review of Biochemistry, 1981
- Reaction Mechanisms of β1H GlobulinInternational Archives of Allergy and Immunology, 1978
- Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution.The Journal of Experimental Medicine, 1977
- Complement activation by the properdin system: formation of a stoichiometric, C3 cleaving complex of properdin factor B with C3bImmunochemistry, 1977
- Third component of human complement: purification from plasma and physicochemical characterizationBiochemistry, 1976
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- ISOLATION OF A FRAGMENT (C3a) OF THE THIRD COMPONENT OF HUMAN COMPLEMENT CONTAINING ANAPHYLATOXIN AND CHEMOTACTIC ACTIVITY AND DESCRIPTION OF AN ANAPHYLATOXIN INACTIVATOR OF HUMAN SERUMThe Journal of Experimental Medicine, 1969
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949