Can visco-elastic phase separation, macromolecular crowding and colloidal physics explain nuclear organisation?
Open Access
- 12 April 2007
- journal article
- Published by Springer Nature in Theoretical Biology and Medical Modelling
- Vol. 4 (1) , 15
- https://doi.org/10.1186/1742-4682-4-15
Abstract
The cell nucleus is highly compartmentalized with well-defined domains, it is not well understood how this nuclear order is maintained. Many scientists are fascinated by the different set of structures observed in the nucleus to attribute functions to them. In order to distinguish functional compartments from non-functional aggregates, I believe is important to investigate the biophysical nature of nuclear organisation.Keywords
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