FURTHER STUDY ON ANTIHYPERTENSIVE ACTION OF BETA-ADRENOCEPTOR BLOCKING-AGENTS IN CONSCIOUS, RENAL HYPERTENSIVE DOGS
- 1 January 1979
- journal article
- research article
- Vol. 242 (1) , 115-127
Abstract
Experiments were conducted out on 7 conscious, renal hypertensive dogs with 7 .beta.-adrenoceptor blocking agents (atenolol, bunitrolol, bunolol, carteolol, nadolol, sotalol and timolol). Three main conclusions were made: the stronger the .beta.-adrenoceptor blocking activity the stronger the antihypertensive action; for the antihypertensive action, very strong .beta.-adrenoceptor blocking activity was needed; d-carteolol, unlike dl-carteolol, had no antihypertensive effect. The .beta.-adrenoceptor blocking action is a prerequisite for the antihypertensive effect of the .beta.-adrenoceptor blocking agents.This publication has 8 references indexed in Scilit:
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