A MODIFICATION OF THE KOELLE TECHNIQUE FOR USE WITH OXIMES
Open Access
- 1 January 1958
- journal article
- research article
- Published by SAGE Publications in Journal of Histochemistry & Cytochemistry
- Vol. 6 (1) , 72-74
- https://doi.org/10.1177/6.1.72
Abstract
The Koelle histochemical method has been modified to study the effect of oximes on cholinesterase activity at motor endplates. It is possible by lowering the pH to hold the reaction between substrate and oxime to a minimum. With this modified procedure, the inhibitory effect of pyridine-2-aldoxime methiodide and diacetylmonoxime on motor endplate cholinesterase can be demonstrated.Keywords
This publication has 3 references indexed in Scilit:
- ON THE CHEMISTRY OF THE THIOCHOLINE METHOD OF KOELLEJournal of Histochemistry & Cytochemistry, 1955
- *ZUR BESTIMMUNG DER AKTIVITAT DER CHOLINESTERASEN IM MENSCHLICHEN BLUTE1954
- THE ELIMINATION OF ENZYMATIC DIFFUSION ARTIFACTS IN THE HISTOCHEMICAL LOCALIZATION OF CHOLINESTERASES AND A SURVEY OF THEIR CELLULAR DISTRIBUTIONS1951