A putative protein of a growth specific cDNA from BALB/C‐3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor
- 4 December 1989
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 258 (2) , 301-304
- https://doi.org/10.1016/0014-5793(89)81679-5
Abstract
A cDNA clone, which represents a species of mRNA that is expressed in growth-stimulated BALB/c-3T3 cells but not in resting cells, was found to encode a protein remarkably similar in sequence to the members of the immunoglobulin superfamily, especially to the extracellular portion of the mouse interleukin 1 receptor. The immunoglobulin superfamily is believed to be involved in cell adhesion and cell-to-cell interaction. The evidence that a member of this family is induced in the course of the initiation of cell proliferation is intriguing.Keywords
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