Molecular cloning and mapping of a human cDNA (SC5DL) encoding a protein homologous to fungal sterol-C5-desaturase
- 1 January 1996
- journal article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 74 (4) , 252-254
- https://doi.org/10.1159/000134427
Abstract
We have isolated a human cDNA clone homologous to fungal ERG3, a gene encoding sterol C-5 desaturase. The full nucleotide sequence of this human cDNA revealed a 708-bp open reading frame that encodes a 236-amino-acid polypeptide. The gene was expressed in all normal human tissues examined. We determined its location to chromosome 11q23.3 by fluorescence in situ hybridization.Keywords
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