Angioma Serpiginosum

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Abstract
Seven [human] cases of angioma serpiginosum are presented. A histological study performed in 6 revealed an increased number of ectatic capillaries in the dermal papillae. One case, a 31 yr old woman, was studied by EM. The dilated capillaries consisted of endothelial cells, pericytes and veil cells. Walls of capillaries showed a heavy precipitation of fine fibrillar material admixed with collagen fibers. Most vessel walls were composed of 2 layers. The inner layer consisted of fine fibrillar material and the outer layer consisted of bundles of collagen fibers of .apprx. 40 nm in diameter. Characteristic findings in the endothelial cells were the formation of accessory lumen or slit-like protrusion of lumen into the endothelial lining. It appeas that angioma serpiginosum is not a simple telangiectasia of preexisting vessels but represents a type of capillary nevus, which has a tendency to manifest itself in the form of capillary dilation and proliferation.

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