Omi/HtrA2 Promotes Cell Death by Binding and Degrading the Anti-apoptotic Protein ped/pea-15
Open Access
- 1 November 2004
- journal article
- Published by Elsevier
- Vol. 279 (45) , 46566-46572
- https://doi.org/10.1074/jbc.m406317200
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Inhibitor of Apoptosis Proteins Are Substrates for the Mitochondrial Serine Protease Omi/HtrA2Journal of Biological Chemistry, 2003
- Protein Kinase B/Akt Binds and Phosphorylates PED/PEA-15, Stabilizing Its Antiapoptotic ActionMolecular and Cellular Biology, 2003
- Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosisGenes & Development, 2003
- Characterization of a Novel and Specific Inhibitor for the Pro-apoptotic Protease Omi/HtrA2Journal of Biological Chemistry, 2003
- Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/OmiNature Structural & Molecular Biology, 2002
- Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase InteractionJournal of Biological Chemistry, 2002
- Caspase Recruitment Domain (Card-Dependent) Cytoplasmic Filaments Mediate Bcl10-Induced Nf-κb ActivationThe Journal of cell biology, 2000
- Proteases to die forGenes & Development, 1998
- Apoptosis by Death FactorCell, 1997
- Improved method for high efficiency transformation of intact yeast cellsNucleic Acids Research, 1992