Gastric Freezing for Peptic Ulceration in Man – A Note of Caution

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Abstract
IN 1962 Wangensteen and his associates1 reported the achievement of "physiological gastrectomy" by gastric freezing. At that time these investigators presented results on 24 patients with duodenal ulcers who were subjected to a one-hour period of gastric freezing. In this group of patients there was excellent subjective relief of symptoms, significant decreases in gastric secretory response and disappearance of duodenal-ulcer craters. In parallel animal studies these workers found that isolated gastric pouches, whether Pavlov, Heidenhain or antral, when frozen for an hour (with inflowing coolant at temperatures of -17 to -20°C.), became unresponsive to physiologic stimuli. They postulated that the . . .

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