LANGERHANS CELLS IN EPITHELIUM OF BOVINE FORESTOMACH - THEIR ROLE IN PRIMARY IMMUNE-RESPONSE

  • 1 January 1977
    • journal article
    • research article
    • Vol. 48  (3) , 187-192
Abstract
Dendritic, migratory, lymphoid cells identical to the Langerhans cells of the epidermis, were found in the epithelium of the bovine forestomach. They possess the characteristic Langerhans cell granules. It can be assumed that these epithelial lymphocytes, (or Langerhans cells) as was reported for the epidermal Langerhans cells, are antigen detectors and form the 1st line of defense in the general immunological response of the body. The Langerhans cells of the forestomach should be named epithelial lymphocytes. The existence of Langerhans cell granules was not previously reported in the epithelial lymphocytes of the true stomach, intestines or respiratory epithelium.

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