The Two Period Binary Response Cross‐Over Trial

1 January 1986

journal article
research article
Published by Wiley in Biometrical Journal

Vol. 28 (7) , 863-869
https://doi.org/10.1002/bimj.4710280715

Abstract

The cross‐over design for clinical trials when responses are binary is discussed. Three tests which have been proposed for the analysis of this problem are compared by an assessment of their assumptions. A simple test to establish whether it is appropriate to include observations from the second period is presented.

Keywords

This publication has 11 references indexed in Scilit:

The Two-Period Crossover Trial
Journal of the Royal Statistical Society: Series D (The Statistician), 1982
The Comparison of Success Rates in Cross-Over Trials in the Presence of an Order Effect
Journal of the Royal Statistical Society Series C: Applied Statistics, 1981
The Crossover Experiment for Clinical Trials
Biometrics, 1980
Model building and testing for the change‐over design
Biometrical Journal, 1980
Testing Hypotheses in the Two‐period Change‐over with Binary Data
Biometrical Journal, 1978
An exact test for comparing matched proportions in crossover designs
Biometrika, 1969
The Two-Period Change-Over Design and Its Use in Clinical Trials
Published by JSTOR ,1965