Trifluoromethanesulphonic acid, as a deprotecting reagent in peptide chemistry

1 January 1974

journal article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 3,p. 107-108
https://doi.org/10.1039/c39740000107

Abstract

Trifluoromethanesulphonic acid was found to cleave, in the presence of anisole, a number of protecting groups currently employed in peptide chemistry without significant side reactions.

Keywords

SIDE
ANISOLE
CLEAVE
DEPROTECTING REAGENT
TRIFLUOROMETHANESULPHONIC ACID
PROTECTING GROUPS
CHEMISTRY TRIFLUOROMETHANESULPHONIC