Orcadian Rhythm of Serotonin Binding in Rat Brain—I. Effect of the Light-Dark Cycle
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Chronobiology International
- Vol. 3 (2) , 135-139
- https://doi.org/10.3109/07420528609066358
Abstract
High affinity serotonin binding to rat brain membranes showed a circadian rhythm with minimal binding at 1000 and a maximal binding at 0000. Brain serotonin levels were almost inverse to the rhythm of serotonin binding. Under reverse light-dark conditions, lights on from 1900 to 0700, a significant phase shift in serotonin binding and concentration of about 8-10 hr was found. The adaptation of the rats to the inverse light-dark cycle was ascertained by plasma ACTH and corticosterone assay.Keywords
This publication has 7 references indexed in Scilit:
- Circadian Variations of Neurotransmitter Binding in Three Age Groups of RatsGerontology, 1985
- Regulation of cerebral serotonin binding and metabolism in sleep-deprived ratsBehavioural Brain Research, 1982
- D-LSD binding to brain homogenates: Possible relationship to serotonin receptorsLife Sciences, 1974
- RADIOIMMUNOASSAY OF STEROIDS IN BIOLOGICAL MATERIALSActa Endocrinologica, 1974
- A simplified method for the quantitative assay of small amounts of protein in biologic materialAnalytical Biochemistry, 1973
- The maturation of the circadian rhythm of brain serotonin in the ratLife Sciences, 1971
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949