Characterization of a Novel Polycystic Kidney Rat Model with Accompanying Polycystic Liver.
- 1 January 2000
- journal article
- Published by Japanese Association for Laboratory Animal Science in Experimental Animals
- Vol. 49 (1) , 51-55
- https://doi.org/10.1538/expanim.49.51
Abstract
A polycystic kidney rat model is being established from a Crj:CD (SD) rat strain. Unlike existing animal models of polycystic kidney disease, this mutant rat has a completely polycystic liver. Mating experiments revealed that the phenotype is controlled by an autosomal recessive gene. We propose that this gene be tentatively called the "rpc" gene.Keywords
This publication has 11 references indexed in Scilit:
- Polycystic kidney disease: Etiology, pathogenesis, and treatmentDisease-a-Month, 1995
- New mouse model for polycystic kidney disease with both recessive and dominant gene effectsKidney International, 1995
- Characterization of the Han:SPRD rat model for hereditary polycystic kidney diseaseKidney International, 1994
- Juvenile cystic kidneys (jck): A new mouse mutation which causes polycystic kidneysKidney International, 1993
- Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney diseasePediatric Nephrology, 1993
- Autosomal-dominant polycystic kidney disease in the ratKidney International, 1993
- Hereditary Polycystic Kidney Disease Associated with Osteorenal Syndrome in RatsVeterinary Pathology, 1989
- A Mutant Rat with Congenital Skeletal Abnormalities and Polycystic KidneysExperimental Animals, 1989
- A New Mouse Model of Genetically Transmitted Polycystic Kidney DiseaseJournal of Urology, 1986
- Murine Congenital Polycystic Kidney Disease: A Model for Studying Development of Cystic DiseaseJournal of Urology, 1982