THE EFFECTS OF PROSTAGLANDINS E1, E2 AND F2αON VAGAL BRADYCARDIA IN THE ANAESTHETIZED MOUSE
Open Access
- 1 September 1975
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 55 (1) , 47-49
- https://doi.org/10.1111/j.1476-5381.1975.tb07608.x
Abstract
1 In anaesthetized mice prostaglandins E1 and E2 reduced the bradycardia caused by electrical stimulation of the sectioned peripheral vagus nerve; prostaglandin F2α produced only a slight inhibition of the vagal response. 2 None of the prostaglandins studied affected acetylcholine-induced bradycardia. 3 Prostaglandins modify para sympathetic nerve activity in vivo presumably by a pre-synaptic action.Keywords
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