Inhibitory effects of anticellular antibodies on colony formation of mouse leukemia L5178YR cells in soft agar
- 1 January 1972
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 18 (1) , 83-86
- https://doi.org/10.1139/m72-013
Abstract
Heat-inactivated antiserum in the absence of complement inhibits colony formation of mouse leukemia L5178YR cells in soft agar. Cells derived from resistant clones in these plates showed the same sensitivity to antiserum as the parent population. Agglutination of the cells was prevented by placing the antiserum dilutions over the cell-containing agar layer. This clearly indicates that cell agglutination by antiserum is not necessarily the essential cause of growth inhibition.Keywords
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