Maximal binding levels of an H1 histone gene-specific factor in S-phase correlate with maximal H1 gene transcription.
Open Access
- 1 October 1988
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 8 (10) , 4576-4578
- https://doi.org/10.1128/mcb.8.10.4576
Abstract
Levels of trans-acting factor (H1-SF) binding to the histone H1 gene-specific motif (5'-AAACACA-3' [L. S. Coles and J. R. E. Wells, Nucleic Acids Res. 13:585-594, 1985]) increase 12-fold from G1 to S-phase in synchronized cells and decrease again in G2 phase of the cell cycle. Since the H1 element is required for S-phase expression of H1 genes (S. Dalton and J. R. E. Wells, EMBO J. 7:49-56, 1988), it is likely that the increased levels of H1-SF binding component play an important role in S-phase regulation of H1 gene transcription.This publication has 12 references indexed in Scilit:
- Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b geneCell, 1987
- Purified transcription factor AP-1 interacts with TPA-inducible enhancer elementsCell, 1987
- Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factorCell, 1987
- Cell cycle regulation of SW15 is required for mother-cell-specific HO transcription in yeastCell, 1987
- Promoters, activator proteins, and the mechanism of transcriptional initiation in yeastCell, 1987
- Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanismCell, 1986
- Transcription of the histone H5 gene is not S-phase regulated.Molecular and Cellular Biology, 1986
- An H1 histone gene-specific 5′ element and evolution of H1 and H5 genesNucleic Acids Research, 1985
- Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5′ elementNucleic Acids Research, 1982
- A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye BindingAnalytical Biochemistry, 1976