THE EFFECT OF THE VAGUS NERVES ON SUGAR TOLERANCE IN DOGS

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Abstract
Bilateral vagotomy above the diaphragm in 7 dogs caused a temporary fall in the normal blood sugar level and a temporary decrease of the sugar tolerance. The peak of the decreased sugar tolerance occurred 3-5 days after vagotomy. The return to normal occurred gradually in 2-3 wks. But in 3 dogs a dummy operation, which left the vagi intact, produced the same change in blood sugar level and sugar tolerance as double vagotomy. Hence it seems clear that the temporary changes in blood sugar and sugar tolerance after section of the vagi nerves are not due to elimination of insulin secretory fibers in the vagi.