Dose response in vivo to digoxin in normo- and hyperkalaemia: associated biochemical changes
- 1 July 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 9 (4) , 515-523
- https://doi.org/10.1093/cvr/9.4.515
Abstract
The effect of digoxin, at two different inotropic levels, was examined in normo- and hyperkalaemic dogs. For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.Keywords
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