C-13 NUCLEAR MAGNETIC-RESONANCE IDENTIFICATION OF 2-HYDROXY-3-0-METHYL-6-BETA-NALTREXOL AS A MINOR NALTREXONE METABOLITE
- 1 January 1978
- journal article
- research article
- Vol. 22 (3) , 455-464
Abstract
A 13C NMR comparison of synthetic and biological samples was used to identify unequivocally 2-hydroxy-3-O-methyl-6.beta.-naltrexol as a minor naltrexone metabolite in humans. The usefulness of natural abundance 13C NMR techniques in metabolism studies was discussed.This publication has 3 references indexed in Scilit:
- IDENTIFICATION AND MEASUREMENT OF 2 NEW METABOLITES OF NALTREXONE IN HUMAN URINE1978
- Ring C conformation of 6.beta.-naltrexol and 6.alpha.-naltrexol. Evidence from proton and carbon-13 nuclear magnetic resonanceThe Journal of Organic Chemistry, 1976
- DISPOSITION OF [15,16-H-3]NALTREXONE IN CENTRAL NERVOUS-SYSTEM OF RAT1976