Clinical evaluation of serum immunoglobulins in amoebiasis.

  • 1 December 1972
    • journal article
    • Vol. 23  (6) , 937-46
Abstract
In eighty-nine adult Nigerians, with clinical and asymptomatic amoebiasis and in patients with conditions other than amoebiasis, serum concentrations of immunoglobulins (G, A and M) are presented as geometric mean values (mg/ml). Statistical analysis revealed a significant relationship between active symptomatic amoebiasis and raised IgG concentrations in all the groups studied except in pregnant and post-partum states. In contrast, analyses of the IgA and IgM data showed no significant correlation except in males with amoebic dysentery; and in males with amoebic liver abscess in which the respective immunoglobulins are significantly raised (Table 1). Estimation of immunoglobulin levels during a follow-up study in fifteen amoebiasis patients showed a tendency for IgG to fall appreciably with treatment of the disease.