THE ROLE OF COPPER IN IRON-METABOLISM
- 1 January 1980
- journal article
- research article
- Vol. 10 (4) , 338-344
Abstract
The various roles played by Cu in Fe metabolism are reviewed. Cu may interfere with Fe absorption by binding to mucosal transferrin. Mobilization of Fe from mucosal, reticuloendothelial and hepatic parenchymal cells may be effected through the action of ceruloplasmin. Cu may participate in heme synthesis through the action of cytochrome oxidase. Reutilization of Fe by the spleen reticuloendothelial cells is subjected to inhibition by excess Cu.This publication has 4 references indexed in Scilit:
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- ROLE OF COPPER IN MITOCHONDRIAL IRON-METABOLISM1976
- KINETIC STUDIES OF FERROUS ION OXIDATION WITH CRYSTALLINE HUMAN FERROXIDASE .2. RATE CONSTANTS AT VARIOUS STEPS AND FORMATION OF A POSSIBLE ENZYME-SUBSTRATE COMPLEX1967
- The Possible Significance of the Ferrous Oxidase Activity of Ceruloplasmin in Normal Human SerumJournal of Biological Chemistry, 1966