RELATIONSHIP BETWEEN RATE OF ELIMINATION OF TUBOCURARINE AND RATE OF DECLINE OF ITS PHARMACOLOGICAL ACTIVITY
Open Access
- 1 November 1964
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 36 (11) , 694-695
- https://doi.org/10.1093/bja/36.11.694
Abstract
It is shown on theoretical grounds that, assuming tubocurarine elimination is an exponential process and the intensity of its pharmacological activity is proportional to the logarithm of the dose, the decline of activity is likely to be linear with time. This conclusion is supported by clinical data.Keywords
This publication has 0 references indexed in Scilit: