[Immunohistochemical and electron microscopic identification of serotonin, melatonin and beta-endorphin in the granules of natural killers].

  • 1 October 1986
    • journal article
    • abstracts
    • Vol. 102  (10) , 491-3
Abstract
The ability of serotonin, melatonin and beta-endorphin synthesis by secreting granules of natural killer cells (NK cells) was established by immunohistochemical method. It was shown that cytotoxic effect of NK cells can be to a certain extent related to the presence of secreting granules. A possible direct contribution of NK cell-synthesized hormones to the natural killer antitumour effect is discussed.

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