Probabilities of Concordance of Twins With Respect to Genetic Markers. A General Formulation

1 April 1979

journal article
research article
Published by Cambridge University Press (CUP) in Acta geneticae medicae et gemellologiae: twin research

Vol. 28 (2) , 125-132
https://doi.org/10.1017/s0001566000009156

Abstract

The formulas needed in the determination of monozygosity in twin pairs using genetic markers are derived and presented. A general formula for the calculation of concordance probabilities independent of gene frequencies and allele number is derived, enabling either manual computation or computer programming for any Mendelian markers usable in twin zygosity diagnosis.

Keywords

TWIN ZYGOSITY DIAGNOSIS
GENETIC MARKERS
CONCORDANCE PROBABILITIES
COMPUTER PROGRAMMING

This publication has 3 references indexed in Scilit:

The diagnosis of zygosity in twins
Behavior Genetics, 1978
Twin Zygosity Diagnosis by Blood Group Antigens
Human Heredity, 1970
MONOZYGOTIC AND DIZYGOTIC TWIN DIAGNOSIS
Annals of Human Genetics, 1955