A Large Outbreak of Mumps in the Postvaccine Era
- 1 December 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 158 (6) , 1253-1260
- https://doi.org/10.1093/infdis/158.6.1253
Abstract
During a county-wide mumps outbreak in Nashville, Tennessee, 332 cases of mumps were identified at a public high school (attack rate, 18.8%). A pep rally 17 d before the peak of the outbreak at a single public high school may have provided an opportunity for point-source exposure. A case-control study demonstrated that vaccine efficacy was 75% (we used provider-verified records and excluded students with a history of mumps disease). Although school records were nonuniform, mumps immunization status was correct, compared with provider-verified records, in at least 85% of both cases and controls. Parental reports were much less reliable. The cost of the outbreak was estimated at $154/case. Receiving mumps vaccine at a vaccine clinic held after the outbreak had peaked was associated with a decrease in risk of mumps disease. Thus, these clinics may have a role in the control of such outbreaks.Keywords
This publication has 11 references indexed in Scilit:
- The epidemiology of mumps in the UK: a preliminary study of virus transmission, herd immunity and the potential impact of immunizationEpidemiology and Infection, 1987
- Effectiveness of Mumps Vaccine in a School OutbreakArchives of Pediatrics & Adolescent Medicine, 1985
- CLINICAL MUMPS VACCINE EFFICACYAmerican Journal of Epidemiology, 1985
- FIELD-EVALUATION OF VACCINE EFFICACY1985
- ON THE NEED FOR THE RARE DISEASE ASSUMPTION IN CASE-CONTROL STUDIESAmerican Journal of Epidemiology, 1982
- EPIDEMIC OF MUMPS IN A PARTIALLY IMMUNE POPULATION1979
- Field evaluation of live virus mumps vaccineThe Journal of Pediatrics, 1968
- Live, Attenuated Mumps-Virus VaccineNew England Journal of Medicine, 1967
- OBSERVATIONS ON A MUMPS EPIDEMIC IN A “VIRGIN” POPULATION1American Journal of Epidemiology, 1959
- MUMPS ORCHITIS AND TESTICULAR ATROPHY. I. OCCURRENCEAnnals of Internal Medicine, 1950