Critical Role for Hypothalamic mTOR Activity in Energy Balance
- 1 April 2009
- journal article
- research article
- Published by Elsevier in Cell Metabolism
- Vol. 9 (4) , 362-374
- https://doi.org/10.1016/j.cmet.2009.03.005
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles ofob/obmiceAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2008
- Disruption of Tsc2 in pancreatic β cells induces β cell mass expansion and improved glucose tolerance in a TORC1-dependent mannerProceedings of the National Academy of Sciences, 2008
- Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and FunctionJournal of Neuroscience, 2008
- Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in miceJournal of Clinical Investigation, 2008
- Biphasic Response of Pancreatic β-Cell Mass to Ablation of Tuberous Sclerosis Complex 2 in MiceMolecular and Cellular Biology, 2008
- The Hormonal Control of Food IntakeCell, 2007
- Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesityJournal of Clinical Investigation, 2006
- Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In VivoMolecular and Cellular Biology, 2006
- TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activityProceedings of the National Academy of Sciences, 2006
- STAT3 signalling is required for leptin regulation of energy balance but not reproductionNature, 2003