Altered Folate Metabolism and Disposition in Mothers Affected by a Spina Bifida Pregnancy: Influence of 677c → t Methylenetetrahydrofolate Reductase and 2756a → g Methionine Synthase Genotypes
- 1 May 2000
- journal article
- Published by Elsevier in Molecular Genetics and Metabolism
- Vol. 70 (1) , 27-44
- https://doi.org/10.1006/mgme.2000.2994
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- A Common Variant in Methionine Synthase Reductase Combined with Low Cobalamin (Vitamin B12) Increases Risk for Spina BifidaMolecular Genetics and Metabolism, 1999
- Impaired Regeneration of Monoglutamyl Tetrahydrofolate Leads to Cellular Folate Depletion in Mothers Affected by a Spina Bifida PregnancyMolecular Genetics and Metabolism, 1998
- Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuriaProceedings of the National Academy of Sciences, 1998
- Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate‐dehydrogenase, methenyltetrahydrofolate‐cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defectsClinical Genetics, 1998
- Methionine synthase and neural tube defects.Journal of Medical Genetics, 1997
- Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifidaThe Lancet, 1995
- A randomised trial of low dose folic acid to prevent neural tube defects. The Irish Vitamin Study Group.Archives of Disease in Childhood, 1992
- Prevention of neural tube defects: Results of the Medical Research Council Vitamin StudyPublished by Elsevier ,1991
- FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCESThe Lancet, 1983
- Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects.BMJ, 1981